Material Safety Data Sheet

ACC# 08100
Section 1 - Chemical Product and Company Identification

MSDS Name: Diphenylamine
Catalog Numbers: S80000, O2611 100, O2611 500, O2611-100, O2611-500, O2611100, O2611500
N-Phenylamiline; Anilinobenzene; N-Phenylbenzeneamine; DPA
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
Emergency Number:
For CHEMTREC assistance, call:
For International CHEMTREC assistance, call:

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
122-39-4 Diphenylamine 100.0 204-539-4

Section 3 - Hazards Identification


Appearance: colorless to grayish solid.
Caution! May cause allergic skin reaction. Causes eye and skin irritation. May be absorbed through intact skin. Causes digestive and respiratory tract irritation. May cause methemoglobinemia. Light sensitive.
Target Organs: Kidneys, central nervous system, liver, red blood cells, bladder.

Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion: May cause irritation of the digestive tract. May cause effects similar to those of acute inhalation.
Inhalation: Inhalation of vapor may cause respiratory tract irritation. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, tachycardia, dyspnea (labored breathing), and death. May cause adverse central nervous system effects including headache, convulsions, and possible death. May cause bladder injury and hypertension.
Chronic: Prolonged or repeated skin contact may cause dermatitis. May cause reproductive and fetal effects. There is a danger of cumulative effects.

Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation. For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood. Cleansing of the entire contaminated area of the body is of utmost importance.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion.
Extinguishing Media: Water or foam may cause frothing. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.
Flash Point: 153 deg C ( 307.40 deg F)
Autoignition Temperature: 634 deg C ( 1,173.20 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 1; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.

Section 7 - Handling and Storage

Handling: Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale. Store protected from light.
Storage: Keep away from sources of ignition. Do not store in direct sunlight. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Diphenylamine 10 mg/m3 TWA 10 mg/m3 TWA none listed

OSHA Vacated PELs: Diphenylamine: 10 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: colorless to grayish
Odor: floral-like
pH: Not available.
Vapor Pressure: 1 mm Hg @ 108 C
Vapor Density: 5.82
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: 576 deg F
Freezing/Melting Point:129 - 131F
Decomposition Temperature:Not available.
Solubility: Negligible in water.
Specific Gravity/Density:1.160
Molecular Formula:C12H11N
Molecular Weight:169.0837

Section 10 - Stability and Reactivity

Chemical Stability: Stable.
Conditions to Avoid: Incompatible materials, light, ignition sources, excess heat.
Incompatibilities with Other Materials: Oxidizing agents, strong acids, isocyanates, hexachloromelamine, organic anhydrides, aldehydes, trichloromelamine.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

CAS# 122-39-4: JJ7800000
CAS# 122-39-4:
     Oral, mouse: LD50 = 1230 mg/kg;
     Oral, rat: LD50 = 1120 mg/kg;

CAS# 122-39-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: Bacteria: Phytobacterium phosphoreum: EC50 =4.77 mg/L; 5,15,30 minutes; Microtox test

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

Shipping Name: Not regulated as a hazardous material No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information


     CAS# 122-39-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     CAS# 122-39-4: Testing required by manufacturers, processors
Section 12b
     CAS# 122-39-4: Section 4
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 122-39-4: immediate, delayed.
Section 313
     This material contains Diphenylamine (CAS# 122-39-4, 100.0%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
     None of the chemicals in this product are considered highly hazardous by OSHA.
     CAS# 122-39-4 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     T N
Risk Phrases:

     R 23/24/25 Toxic by inhalation, in contact with skin and if
     R 33 Danger of cumulative effects.
     R 50/53 Very toxic to aquatic organisms, may cause long-term
     adverse effects in the aquatic environment.

Safety Phrases:

     S 28 After contact with skin, wash immediately with...
     S 36/37 Wear suitable protective clothing and gloves.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 60 This material and its container must be disposed of as hazardou
     s waste.
     S 61 Avoid release to the environment. Refer to special instructions
     /safety data sheets.

WGK (Water Danger/Protection)

     CAS# 122-39-4: 3
Canada - DSL/NDSL
     CAS# 122-39-4 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 122-39-4 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 6/16/1999
Revision #3 Date: 10/03/2005

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.