Enroll in Phage Hunters Lab for Fall 2017/Spring 2018
Replaces the regular lab component of BIO 111 General biology I, section 106P(fall) and BIO 112 (spring)
We are looking for bright, motivated students who are interested in conducting discovery-based undergraduate research. This unique mentored research experience is a national experiment sponsored by the Howard Hughes Medical Research Institute (HHMI).
Space is limited to 18 students.
- Full-year commitment preferred (fall and spring semesters)
Lecture: Mondays and Wednesdays, 8–9:15 a.m.
Lab: Mondays and Wednesdays, 9:30–11:10 a.m.
- Be excited about scientific research
|Michael Herrera, 31, and Roselyn Barahona, 18, presented their research describing the characterization of two novel phages that are isolated in the gardens of North Carolina at the ninth annual SEA-PHAGES Symposium at the Howard Hughes Medical Institute in Ashburn, Virginia. Read more|
We will start the fall semester by digging in soil to isolate new bacteriophages (viruses that infect bacteria). Viruses will be characterized in the lab using microbiology and molecular biology techniques and sent for sequencing over winter break.
When we return for the spring semester we will analyze our newly sequenced viral genomes using bioinformatics approaches.
|Part 1: Phage Discovery|
|Fall||Isolate, characterize, purify phage
|EM at UNC-CH||Isolate and purify DNA||Characterize DNA||Send to sequencing center
Late Nov./Early Dec.
|BREAK||Genomes are sequenced and assembled off-site during the winter recess
|Part 2: Phage Genome Annotation|
|Spring||Genome sequences returned
|Genomes organized and annotated||Post-annotation phage exeriments||Novel sequences named and subitted to GenBank